Watch & Listen

Omega-3 and Brain Injury Recovery

A podcast of Dr. Lewis with previous patient John Miles

Real Recoveries

Hope After Months of Concussion Symptoms- July 2026

β€œI wanted to drop you a line to let you know about the relief I have already experienced in the first 4 days of treatment with the Omega oil. I have suffered from concussion symptoms for the past 10-12 months. First I had a car accident in July 2025 then a fall in October of 2025 where I fractured the bone under my eye. The pressure in my head along with light sensitivity, vertigo, inability to fall asleep have tormented me (and was getting worse) and nothing helped. I began to see results immediately. Although the symptoms have not gone away completely, I feel a change in the pressure and vertigo. I was amazed at how fast it worked for me. Thank you Ashley for recommending this treatment and I look forward to complete healing.”

L.H. -Brain Performance Protocol

From Concussion to Feeling Like Herself Again: Maddison’s Story πŸ™Œ

Maddison, a preschool teacher, suffered a concussion just before Christmas 2025. In the weeks that followed, she dealt with headaches, brain fog, and sensitivity to light and noise that made both work and daily life challenging.

She also had a long history of chronic migraines that she had managed for years, but they continued to affect her quality of life.

After starting her personalized protocol with BHERI, she noticed changes within the first weekβ€”her post-concussion symptoms began to ease and her clarity started to return.

Over the next few months, her improvement continued. Most significantly, her chronic migraines resolved, and she is now 3 months migraine-free.

Today, she’s back in the classroom and feeling like herself again.

Real People. Real Results.

Every recovery journey is different, and every improvement is worth celebrating.

Below are symptom score improvements from some clients who participated in BHERI’s Brain Performance Program in 2026.

  • πŸ“ˆ 62% improvement (Symptom score: 93 β†’ 35)
  • πŸ“ˆ 62% improvement (Symptom score: 90 β†’ 34)
  • πŸ“ˆ 52% improvement (Symptom score: 115 β†’ 55)
  • πŸ“ˆ 47% improvement (Symptom score: 85 β†’ 45)
  • πŸ“ˆ 44% improvement (Symptom score: 25 β†’ 14)
  • πŸ“ˆ 37% improvement (Symptom score: 35 β†’ 22)
  • πŸ“ˆ 36% improvement (Symptom score: 88 β†’ 56)
  • πŸ“ˆ 17% improvement (Symptom score: 91 β†’ 75)

While every person’s path is unique, these outcomes highlight the meaningful progress that can occur with consistent care and individualized support. We’re grateful to be part of each client’s journey and look forward to sharing more success stories as they continue.

Brain Performance Program Spotlight – June 2026

After just one month on the Brain Performance Protocol, our client reached out to share the real changes she’s noticed in multiple areas of her life.

“I honestly feel like these supplements have made a real difference for me. I’ve been crying less, sleeping better, and overall I feel more emotionally stable. Life has brought some really low moments lately, but I’ve been able to handle them so much better than I used to. Instead of completely breaking down, I’ve been able to work through my emotions and bring myself back up. I truly feel like these supplements have helped improve my mental health, and I’m so grateful for the difference they’ve made.”

A.R.

Brain Performance Program

The Published Science

Chronic Stress, the HPA Axis, and Omega-3: Anti-Inflammatory and Cortisol Effects (with honest limits)

Multiple · 2017

Covers evidence that omega-3s suppress proinflammatory cytokines and can blunt cortisol responses to stress via the HPA axis - while transparently noting mixed human results, including a trial where chronic psychological stress was NOT ameliorated by EPA alone. Included deliberately to model BHERI's honest, applied-research approach to evidence.

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Omega-3 PUFAs and the Gut-Brain Axis in Depression: Immune Resolution and HPA Modulation

Review · 2025

Synthesizes how EPA and DHA may exert effects through the gut-brain axis - shaping microbiota, reducing intestinal permeability and immune activation, and modulating HPA-axis stress signaling. Notes individuals with mood disorders often show reduced EPA/DHA membrane levels. Presented as mechanism and active inquiry, not settled cure.

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Neuroinflammation in PTSD: Cytokines, the Blood-Brain Barrier, and Microglial Activation

Review · 2025

Documents that PTSD patients show elevated IL-1B, IL-6, TNF-a, and C-reactive protein, and that circulating cytokines cross a weakened blood-brain barrier to activate microglia - a neuroinflammatory loop damaging emotion-processing circuits. Much of the impetus comes from studies in US veterans, BHERI's core population.

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Crosstalk Between Inflammatory and Neural Signaling in Post-Traumatic Stress Disorder (PTSD)

Review · 2023

Links psychological trauma to the same neuroinflammatory machinery as physical brain injury: disruption of the HPA axis alongside elevated proinflammatory cytokines and COX-2 metabolites worsens PTSD. Supports BHERI's view that trauma - physical or psychological - converges on neuroinflammation that the omega-3 protocol is designed to address.

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Luminal Bioavailability of Orally Administered Omega-3 PUFAs in the Distal Small Intestine

Watson H, et al. · 2021

A human study measuring the intestinal bioavailability of 4g/day EPA+DHA over 28 days and its effect on the gut microbiome. Adds direct human absorption data underpinning BHERI's dosing and gut-health-aware protocol design.

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Polyphenol Microbial Metabolites Exhibit Gut and Blood-Brain Barrier Permeability and Protect Microglia Against Inflammation

Wang D, et al. · 2019

Shows that polyphenol microbial metabolites cross both the gut and blood-brain barriers more readily than their parent compounds and protect brain microglia against inflammation. Provides the scientific basis for BHERI's pairing of polyphenols with the omega-3 protocol to aid blood-brain-barrier delivery.

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Associations Among Dietary Omega-3 PUFAs, the Gut Microbiota, and Intestinal Immunity

Fu Y, et al. · 2021

Demonstrates that the gut microbiota modulates the absorption and metabolism of omega-3 PUFAs, and that omega-3 intake improves the microbiome by increasing beneficial bacteria. Supports BHERI's view that gut health is a determinant of how effectively the omega-3 protocol is absorbed and utilized.

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Molecular Mechanisms Linking Omega-3 Fatty Acids and the Gut-Brain Axis

Dolan-Evans, et al. · 2025

Explains how EPA and DHA preserve the integrity of both the intestinal and blood-brain barriers, modulate inflammation by reducing proinflammatory cytokines, and regulate the HPA axis by reducing excessive cortisol. Provides the mechanistic foundation for BHERI's emphasis on gut health in protocol absorption.

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Omega-3 Fatty Acids and Traumatic Neurological Injury: From Neuroprotection to Neuroplasticity

Michael-Titus AT, Priestley JV · 2014

Reviews evidence that omega-3 PUFA intervention is a promising approach for acute traumatic CNS injury, with neuroprotection magnitude comparable to other agents with good translational profiles. Extends the rationale from protection to active neuroplasticity and repair.

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High-Dose Omega-3 Fatty Acids in the Treatment of Sport-Related Concussions

Clinical trial (Brain Armor) · 2013

A clinical trial evaluating whether high-dose omega-3 supplementation improves recoverability in athletes who have sustained a concussion, with the explicit aim of reducing recovery time and potentially the incidence of post-concussion syndrome - directly aligned with BHERI's Acute Concussion Care program.

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OPTIMA-TBI: A Randomized, Placebo-Controlled Trial of Omega-3 in TBI

OPTIMA-TBI Study Group · 2020

An active randomized, placebo-controlled, double-blinded trial testing 6g/day of DHA+EPA for one month followed by 1.2g/day - a high-dose protocol resembling BHERI's saturation approach. Measures biomarkers of neuronal injury, inflammation, and neurogenesis. Represents the rigorous trial work now validating the approach BHERI has applied clinically.

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Omega-3 Fatty Acids as a Putative Treatment for Traumatic Brain Injury (Review)

Hasadsri L, et al. · 2013

A comprehensive review concluding that DHA and EPA have the most promising laboratory evidence for neuro-restorative capacity in TBI, with both animal and human studies suggesting benefit. Honestly notes the field still requires large clinical trials - consistent with BHERI's applied-research posture.

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Use of Omega-3s in Traumatic Brain Injury

Lewis MD · 2017

A review by Dr. Lewis summarizing the case for omega-3 fatty acids in TBI, noting that clinical research has not identified a single effective treatment strategy for TBI when a combined approach to neuroprotection, neuroinflammation, and neuroregeneration is needed - an approach omega-3s uniquely offer. Also addresses the unfounded bleeding-risk concern.

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Therapeutic Use of Omega-3 Fatty Acids in Severe Head Trauma

Lewis M, Ghassemi P, Hibbeln J · 2013

Dr. Lewis and colleagues document the therapeutic application of high-dose omega-3 fatty acids in severe head trauma, drawing on the principle that the injured brain requires the omega-3 building blocks it is made of in order to repair. Part of the published basis for BHERI's protocol.

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Neuroprotection for the Warrior: Dietary Supplementation with Omega-3 Fatty Acids

Lewis MD, Bailes J · 2011

A foundational paper by BHERI founder Dr. Michael Lewis and neurosurgeon Dr. Julian Bailes making the case for omega-3 supplementation as neuroprotection for service members at risk of traumatic brain injury. Establishes the rationale that DHA and EPA, as primary structural components of brain tissue, support resilience to and recovery from neurotrauma.

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